Inventors of the MouseOx® Small Animal Vital Signs Monitor Publications
Peer Reviewed Publications Utilizing
The MouseOx™ Pulse Oximeter
Through December 2011
Total Publications: 148
- Influenza, Pneumonia, RSV & Other Acute Respiratory Disorders
- Lung Injury & Mechanical Ventilation
- Lung Cancer, COPD, Sleep Apnea & Other Chronic Respiratory Disorders
- Shock Models
- Stroke & Brain Injury
- Hypertension, Hypotension & Other Cardiovascular Disorders
- Hypoxia & Inhalation Studies
- Vital Signs Monitoring During Imaging
- Vital Signs Monitoring During Surgery & Experiments Requiring Anesthesia
- Pharmacology & Toxicology
- Anesthesia and Surgical Research
1. Influenza, Pneumonia, RSV & Other Acute Respiratory Disorders
Pulse-oximetry accurately predicts lung pathology and the immune response during influenza infection
- ►Virology. 2009 Jun 1.
Verhoeven D, Teijaro JR, Farber DL. Department of Surgery, University of Maryland School of Medicine, Baltimore, MD 21210, USA.
In animal models of influenza, systemic weight loss is the primary indicator of morbidity from infection, which does not assess local lung pathology or the immune response. Here, we used a mouse-adapted pulse-oximeter as a non-invasive clinical readout of lung function during influenza infection in mice, and found direct correlations between oxygen saturation levels and lung pathology, that reflected the morbidity and survival from influenza infection. We found blood oxygen levels to be a more accurate assessment than weight-loss morbidity in predicting lung pathology in hosts infected with different viral doses, and in assessing immune-mediated viral clearance in the lung.
Post-infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection
- ►ajrcmb.org
IC Davis, ER Lazarowski, FP Chen, JM Hickman-Davis … - American Journal of Respiratory Cell and Molecular Biology, 2007 - Am Thoracic Soc
... Peripheral Blood Arterial Oxygen Saturation Sp O 2 was measured in conscious mice
using the MouseOx system (Starr Life Sciences Corp., Allison Park, PA), in ...
Cited by 6 - Related articles - Web Search - BL Direct - All 4 versions
Low Dose Arsenic Compromises the Immune Response to Influenza A Infection in vivo
CD Kozul, KH Ely, RI Enelow, JW Hamilton - ehponline.org
... SpO 2 was measured using the MouseOx system (Starr Life Sciences Corp.,
Allison Park, PA) according to manufacturer’s protocol. ...
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Because an increased severity of influenza infection often correlates with a decrease in SpO2, we measured the oxygen saturation levels in infected control and As-exposed conscious mice at day 7 p.i. The As-exposed mice displayed a significant decrease in SpO2 levels compared with control mice (Figure 3D). The average SpO2 reading for the control mice infected with influenza was 95.2% (range, 93–97.5%), and the average SpO2 reading for As-exposed mice infected with influenza was 82.9% (range, 75–90%). Three of the six As-exposed mice had SpO2 readings considered to be dangerously low (i.e., ≤ 80%).
Differential Pathogenesis of Respiratory Syncytial Virus Clinical Isolates in BALB/c Mice
KL Stokes, MH Chi, K Sakamoto… - Journal of …, 2011 - Am Soc Microbiol
... The anesthetized mouse's feet were restrained to a pad with tape. A rodent pulse oximeter
(MouseOx; Starr Life Sciences Corp., Oakmont, PA) was used. The MouseOx sensor was applied
to the mouse's thigh, and the mouse was covered with a cloth to reduce ambient light. ...
Cited by 2 - Related articles - All 4 versions
[PDF] from umich.eduSM Coomes - 2011 - deepblue.lib.umich.edu
Page 1. Pulmonary gammaherpesvirus infection and pneumonitis development
following murine bone marrow transplant by Stephanie Michael Coomes A
dissertation submitted in partial fulfillment of the requirements for the ...
Related articles
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus
LA Monticelli, GF Sonnenberg, MC Abt… - Nature …, 2011 - nature.com
Cytokine-producing innate lymphoid cells are found at mucosal surfaces. Artis
and Wherry and their colleagues show that innate 'nuocyte-like' cells accumulate
in virus-infected lungs and contribute to the repair of tissues.
All 3 versions
2. Lung Injury & Mechanical Ventilation
Effects of Ethanol on Pulmonary Inflammation in Postburn Intratracheal Infection.
- ►burncareresearch.org
EL Murdoch, HG Brown, RL Gamelli, EJ Kovacs - Journal of Burn Care & Research, 2008 - burncareresearch.org
... We used a murine pulse oximeter (MouseOx, STARR Life Science Corp., Allison Park,
PA), which allowed us to perform this noninvasive procedure on unanesthetized ...
Cited by 2 - Related articles - Cached - Web Search - BL Direct - All 3 versions
Infectious complications are a major cause of mortality in trauma patients. Burn patients with prior ethanol exposure have a worse prognosis than those who sustain injury but had not been drinking. We examined pulmonary infection and lung pathology in mice given ethanol (1.2 g/kg) 30 minutes before being subjected to 13 to 15% total body surface area scald burn followed by intratracheal inoculation with Pseudomonas aeruginosa (1-2 × 103 colony-forming units [CFUs]). Survival was monitored for up to 48 hours. Sham control groups had 100% survival after intratracheal infection regardless of ethanol exposure. Infected burned animals had 55% survival; however, survival of infected mice exposed to ethanol and burn injury was significantly lower (27%, P < .0001). When pulmonary infection was evaluated, the lungs of sham groups were negative for bacterial colonies. In addition, at 24 hours there were no significant differences in lung CFUs from infected burned animals regardless of ethanol exposure (3.0 × 104). However, pulmonary bacterial content significantly decreased (1.2 × 10, P < .02) at 48 hours in mice given burn injury alone, where CFUs from the lungs of mice exposed to ethanol prior to burn did not decline (5.4 × 105). At the same time point, lungs from animals given ethanol and burn injury had about a 2-fold (P < .02) increase in leukocyte infiltration and vascular congestion, as well as decreased pulmonary oxygen saturation (82.8%, P < .02), when compared with other treatment groups. In summary, ethanol exposure in postburn intratracheal infection results in the inability to clear pulmonary infection marked by a prolonged pulmonary leukocyte accumulation and a decrease in pulmonary function.
Therapeutic effects of hypercapnia on chronic lung injury and vascular remodeling in neonatal rats
A Masood, M Yi, M Lau, R Belcastro, S … - American Journal of …, 2009 - Am Physiological Soc
... clinical analyzer (Abbott Diagnostics, Abbott Park, IL). Effects of anesthesia on heart
and respiratory rates were assessed using a tail sensor pulse oximeter (MouseOx;
STARR Life Sciences, Oakmont, PA). Immunohistochemistry. ...
Cited by 1 - Related articles - All 5 versions
Transfusion-related acute lung injury
CA Sheppard, LE Lögdberg, JC Zimring, CD Hillyer - Hematology/oncology clinics of North America, 2007 - Elsevier
... Application of new tools, such as the recently marketed mouse pulse oximeter (MouseOx,
Starr Life Sciences Corp., Allison Perk, PA), may facilitate a ...
Cited by 9 - Related articles - Web Search - All 6 versions
Comparison of the effect of LPS and PAM3 on ventilated lungs
H Hauber, D Karp, T Goldmann, E … - BMC Pulmonary …, 2010 - biomedcentral.com
... computer-controlled small animal ventilator. Oxygen saturation and pulse rate were monitored
using the MouseOx oximeter (Starr Life Science, Pittburgh, PA). The sensor was placed on the
back leg along the leg axis. The mice were covered throughout the experiments ...
Effect of low tidal volume ventilation on lung function and inflammation in mice
HP Hauber, D Karp, T Goldmann, E … - BMC Pulmonary …, 2010 - biomedcentral.com
... Oxygen saturation and pulse rate were monitored using the MouseOx oximeter (Starr Life Science,
Pittburgh, PA). The sensor was placed on the back leg along the leg axis. The mice were covered
throughout the experiments to maintain body temperature. Protocols. ...
Lung volume recruitment maneuvers and respiratory system mechanics in mechanically ventilated mice
V Cannizzaro, LJ Berry, PK Nicholls, GR Zosky, … - Respiratory physiology …, 2009 - Elsevier
... Heart rate and transcutaneous oxygen saturation were monitored via a small animal pulse
oximeter (MouseOx™, STARR Life Sciences Corporation™, Oakmont, PA, USA) by placing the
non-invasive sensor on the tail. 2.2. Measurement of respiratory system mechanics. ...
Cited by 1 - All 3 versions
Chronic hypercapnia alters lung matrix composition in mouse pups
J Ryu, GP Heldt, M Nguyen, O … - Journal of Applied …, 2010 - Am Physiological Soc
... on 120 unrestrained un-anaesthetized mice either in room air or in the hypercapnia
chamber using the 121 MouseOx system (Starr Life Sciences Corp, Oakmont, PA)
as per manufacture's instruction. 122 Data was collected ...
RESPIRATORY MECHANICS IN INFANT AND ADULT MICE MODELLING VENTILATOR-INDUCED LUNG INJURY
V CANNIZZARO - phd.szote.u-szeged.hu
... PEEP=2 cmH2O. Heart rate and transcutaneous oxygen saturation were monitored via a small
animal pulse oximeter (MouseOxTM, STARR Life Sciences CorporationTM, Oakmont PA, USA)
by placing the non-invasive sensor on the tail. Animals were then ...
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D Wang, JE Morales, DG Calame, JL Alcorn, RA … - Molecular …, 2010 - nature.com
... (b) Shown graphically are the blood arterial oxygen saturation levels recorded on days 4, 7, and
10 after BLM-challenge using a small rodent oximeter sensor mounted on the thigh of each mouse
(Mouse OX ; STARR Life Sciences) as described in Materials and Methods. ...
Cited by 1 - Related articles - All 4 versions
H Li, X Su, X Yan, K Wasserloos, W Chao… - …, 2010 - journals.lww.com
... The oxygen saturation and heart rate in the anesthetized mice were continuously monitored with
MouseOx (Starr Life Science Corp., Oakmont, PA) and maintained within physiologic range with
supplement of ox- ygen and intraperitoneal administration of glycopyrrolate (0.01 μg ...
Related articles - All 5 versions
Simvastatin attenuates ventilator-induced lung injury in mice
H Muller, K Hellwig, S Rosseau, T Tschernig… - Critical …, 2010 - biomedcentral.com
Page 1. RESEARCH Open Access Simvastatin attenuates ventilator-induced lung
injury in mice Holger C Müller1*, Katharina Hellwig1, Simone Rosseau1, Thomas
Tschernig2, Andreas Schmiedl3, Birgitt Gutbier1, Bernd Schmeck1 ...
Cited by 2 - Related articles - View as HTML - All 8 versions
Inducible disruption of autophagy in the lung causes airway hyper-responsiveness
D Inoue, H Kubo, K Taguchi, T Suzuki… - Biochemical and …, 2010 - Elsevier
... The weight of the male micewasmeasured every four weeks for 16 weeks, after
starting doxycycline treatment. Oxygen saturation (SpO2) was measured by pulse
oxymetry, the Mouse Oxsystem (Starr Life Science Corp). Mice ...
V Cannizzaro, LJ Berry, PK Nicholls… - 2010 - researchrepository.murdoch.edu.au
... 90/min, VT of ~ 7 mL/kg, and PEEP 3 cmH2O. Heart rate and transcutaneous oxygen saturation
(StcO2) were monitored via oximeter (MouseOx TM , STARR Life Sciences Corporation TM ,
Oakmont PA, USA) by placing a non-invasive sensor on the tail. ...
View as HTML
High Tidal Volume Ventilation Is not Deleterious in Infant Rats Exposed to Severe Hemorrhage
V Cannizzaro, LJ Berry, PK Nicholls… - The Journal of …, 2010 - pdfs.journals.lww.com
... 3 cm H2O. Heart rate and transcutaneous oxygen saturation (StcO2) were monitored
via oximeter (MouseOx; STARR Life Sciences Corp., Oakmont, PA) by placing a
noninvasive sensor on the tail. Measurement of Respiratory ...
Related articles - All 5 versions
Pulmonary Surfactant Surface Tension Influences Alveolar Capillary Shape and Oxygenation
M Ikegami, TE Weaver, SN Grant… - American journal of …, 2009 - ncbi.nlm.nih.gov
... Oxygen Saturation. Sequential measurements of percent oxygen saturation of arterial hemoglobin
(Sp O 2 ) were made in room air by using a small-animal pulse oximeter (MouseOx; Starr Life
Sciences Corp., Allison Park, PA) according to the manufacturer's instructions. ...
Cited by 1 - Related articles - All 4 versions
MITIGATION OF CHLORINE GAS LUNG INJURY IN RATS BY POST EXPOSURE ADMINISTRATION OF SODIUM NITRITE
AK Yadav, SF Doran, AA Samal… - American Journal of …, 2010 - Am Physiological Soc
... Peripheral oxygen saturations were measured with a MouseOx Small Animal Oxymeter (STARR
Life Sciences, Allison Park, PA) connected to a personal computer equipped with analysis software. ...
C and D= Peripheral Oxygen Saturations (STARR Life Corp MouseOx Small ...
Pre-Exposure to Hyperoxia Causes Increased Lung Injury and Epithelial Apoptosis in Mice Ventilated with High Tidal Volumes
PS Makena, CL Luellen, L Balazs… - American Journal of …, 2010 - Am Physiological Soc
Related articles - All 2 versions
Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite
AK Yadav, SF Doran, AA Samal… - American Journal of …, 2011 - Am Physiological Soc
... Peripheral oxygen saturations were measured with a MouseOx Small Animal Oxymeter
(STARR Life Sciences, Allison Park, PA) connected to a personal computer equipped
with analysis software. The sensor was placed on the rat tail. ...
Cited by 1 - Related articles - All 4 versions
Rescue of murine silica-induced lung injury and fibrosis by human embryonic stem cells
P Spitalieri, MC Quitadamo, A Orlandi… - European …, 2011 - Eur Respiratory Soc
... Oxygen saturation Blood arterial oxygen saturation was recorded using a small rodent oximeter
sensor mounted on the thigh of each experimental animal (MouseOX; STARR Life Sciences,
Oakmont, PA). Three groups of animals were recorded, each containing 5 mice. ...
Related articles - All 2 versions
3. Lung Cancer, COPD, Sleep Apnea & Other Chronic Respiratory Disorders
Non-invasive diagnosis of early pulmonary disease in PECAM-deficient mice using infrared …
MA Early, M Lishnevsky, JM Gilchrist, DM … - Experimental and Molecular Pathology, 2009 - Elsevier
... Pulse oximetry. This study used the MouseOx system (Starr Life Sciences, Oakmont,
PA). Conscious (non-anesthetized) mice were used in all studies. ...
Pulse oximetry is a common tool for detecting reduced pulmonary function in human interstitial lung diseases. It has not previously been used in a mouse model of interstitial lung disease. Further, platelet endothelial cell adhesion molecule deficient mice rarely show symptoms until disease is advanced.
Using blood oxygen saturation, different stages of disease could be identified in a non-invasive manner. These stages could be correlated to pathology. Collagen deposition, using Picrosirius Red, did correlate with blood oxygen saturation. These studies are the first to show the use of an infrared pulse oximetry system to analyze the progression of a fibrotic interstitial lung disease in a mouse model of the human diseases. Further, these studies show that an early alveolar damage/enlargement event precedes the fibrosis in this mouse model, a stage that represents the best targets for disease analysis and prevention. This stage does not have extensive collagen deposition. Most importantly, targeting this earliest stage of disease for therapeutic intervention may lead to novel treatment for human disease.
RS GN - 2008 - assets0.pubget.com
Page 1. JPET #144311 1 Aerosolized Phosphoinositide 3-Kinase γ/δ Inhibitor TG100-115 as
a Therapeutic Candidate for Asthma and Chronic Obstructive Pulmonary Disease John Doukas,
Lisa Eide, Karin Stebbins, Adrienne Racanelli-Layton, Luis Dellamary, Michael ...
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[BOOK] Integration in respiratory control: from genes to systems
MJ Poulin, RJA Wilson - 2007 - books.google.com
... National Research Council Research Press (Canada) Novus Biologicals, Inc. Physiological
Measurement Springer Publishing STARR Life Sciences Corp Page 16. . ...
All 3 versions
Moderate pulmonary arterial hypertension in male mice lacking the vasoactive intestinal peptide gene
- ►ahajournals.org
SI Said, SA Hamidi, KG Dickman, AM Szema, S … - Circulation, 2007 - Am Heart Assoc
... We confirmed these measurements by determining hemoglobin O 2 saturation 25 by a
special mouse oximeter (Starr Life Sciences, Allison Park, Pa) applied to the ...
Cited by 22 - Related articles - Web Search - All 4 versions
Blunted hypoxic pulmonary vasoconstriction in experimental neonatal chronic lung disease
171.66.122.149 [HTML]GJ Rey-Parra, SL Archer, RD Bland, KH … - American journal of …, 2008 - 171.66.122.149
... peak as previously described (26). For the HPV challenge, animals were briefly (
30 s) exposed to hypoxia (2.5% O 2 ) until a saturation of approximately 60%
(MouseOx; Starr Life Sciences Corp., Oakmont, PA) was obtained. ...
Cited by 3 - Related articles - All 12 versions
Breathing and sleep: Measurement methods, genetic influences, and developmental impacts
DM Baekey, P Feng, MJ Decker, KP Strohl - ILAR J, 2009 - dels.nas.edu
... Hb saturation and heart rate were moni- tored with a MouseOx rodent pulse oximeter (Starr Life
Sciences, Oakmont, PA), environmental O2 concentration with an Alpha- Omega 9500 series
oxygen monitor, and all signals were recorded using a CED 1401 data acquisition ...
Cited by 3 - Related articles - View as HTML - All 4 versions
The Asparaginyl Hydroxylase Factor Inhibiting HIF-1 [alpha] Is an Essential Regulator of Metabolism
N Zhang, Z Fu, S Linke, J Chicher, JJ Gorman, DA Visk, … - Cell Metabolism, 2010 - Elsevier
The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice
RE Nisbet, AS Graves, DJ Kleinhenz… - American journal of …, 2009 - ncbi.nlm.nih.gov
... chamber with room air. Alterations in oxyhemoglobin saturation of mice in the CIH
chamber were monitored with a pulse oximeter specifically designed for rodents
(MouseOX; Starr Life Sciences, Oakinant, PA). In preliminary studies ...
Cited by 7 - Related articles - All 6 versions
Non-invasive system for applying airway obstructions to model obstructive sleep apnea in mice
A Carreras, Y Wang, D Gozal, JM Montserrat… - Respiratory Physiology …, 2010 - Elsevier
... 2 ) swings found in patients with OSA. After each animal was placed on the apnea
platform, and prior to enclosing it in the box, a pulse oxymeter (MouseOx; STARR
Life Sciences Corp. Oakmont, PA, USA) was placed on its ...
D Pal, WJ Lipinski, AJ Walker, AM Turner… - …, 2011 - journals.lww.com
... Mean sevoflurane concentration required to achieve 50% burst suppression was 3.38 ± 0.03%
(range: 2.9–3.8). The heart rate, respiratory rate, and oxygen saturation were continuously
monitored using a MouseOx® monitor (Starr Life Sciences, Oakmont, PA). ...
Cited by 7 - Related articles - All 3 versions
4. Shock Models
A Olivera, C Eisner, Y Kitamura, S Dillahunt, L Allende, … - 2010 - ncbi.nlm.nih.gov
[HTML] Ambient oxygen promotes tumorigenesis
[HTML] from plos.orgHJ Sung, W Ma, MF Starost, CU Lago, PK Lim… - PloS one, 2011 - dx.plos.org
... Blood oxygen saturation measurement. Arterial blood oxygen saturation was
determined using a pulse oximetry sensor (MouseOx™ Oxymeter, STARR Life
Sciences Corp.) attached to the tail of 10% oxygen acclimated mice. ...
Cited by 1 - Related articles - Cached - All 7 versions
5. Stroke & Brain Injury
Postischemic Brain Injury Is Attenuated in Mice Lacking the {beta} 2-Adrenergic Receptor
- ►anesth-analg.org
RQ Han, YB Ouyang, L Xu, R Agrawal, AJ Patterson, … - Anesthesia & Analgesia, 2009 - anesth-analg.org
... Pulse oximetry (Spo 2 ), heart rate, and respiratory rate were monitored
continuously (STARR life sciences Corp., Allison Park, PA). ...
Cited by 1 - Related articles - Web Search - All 13 versions
Reproductive age modulates the impact of focal ischemia on the forebrain as well as the effects of …
A Selvamani, F Sohrabji - Neurobiology of Aging, 2008 - Elsevier
... were maintained at 37 °C throughout, and respiratory rate and oxygen saturation
were constantly monitored using the Mouse Oximeter (STARR Life Sciences Corp ...
Cited by 1 - Related articles - Web Search - All 5 versions
A Sigler, A Goroshkov, TH Murphy - Journal of neuroscience methods, 2008 - Elsevier
... The physiological parameters mentioned above were measured using a Mouse-Ox pulse oximeter
(Starr Life Sciences, Oakmont, PA). Hydration was maintained by intraperitoneal injection of saline
(100–200 μl) with 20 mM glucose at 1–2 h intervals. 2.2. Stroke model. ...
Cited by 6 - Related articles - All 6 versions
Novel Model of Frontal Impact Closed Head Injury in the Rat
M Kilbourne, R Kuehn, C Tosun, J Caridi, K … - Journal of …, 2009 - liebertonline.com
... After injury, the coupling arm was removed and the infraorbital incisions were closed. Oxygen
saturation and heart rate were monitored pre- and post-injury using a pulse oximeter (Mouse
Ox ™ ; STARR Life Sciences Corp., Oakmont, PA) placed on a hindlimb. ...
All 4 versions
JC Chang, LL Shook, J Biag, EN Nguyen, AW Toga, … - Brain, 2010 - Oxford Univ Press
... of 2–7 s. In selected experiments, heart rate, pulse oxygenation and respiratory rate were
monitored using a pulse oximeter (three animals with Nonin 8600 V, Nonin Inc., Minneapolis,
MN, USA and four animals with MouseOx, Starr Life Sciences Corp., Oakmont, PA, USA). ...
Cited by 1
Recombinant Fv-Hsp70 Protein Mediates Neuroprotection After Focal Cerebral Ischemia in Rats
X Zhan, BP Ander, IH Liao, JE Hansen, C Kim, D … - Stroke, 2010 - Am Heart Assoc
... Heart rate, breathing rate, and SpO 2 were measured using the MouseOx Murine Pulse
Oximeter System (Starr Life Sciences Corp; Oakmont, Pa). Cerebral blood flow was measured
using a Laser Doppler Monitor (Perimed Inc; Ventura, Calif). 13. ...
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Nimodipine Prevents Memory Impairment Caused by Nitroglycerin-Induced Hypotension in Adult Mice
anesth-analg.net [HTML]A Bekker, M Haile, YS Li, S Galoyan, E … - Anesthesia & …, 2009 - anesth-analg.net
... acquisition system (ADInstruments, Sydney, Australia). A MouseOx pulse oximetry device
(STARR Life Sciences, Allison Park, PA) was used to measure oxygen saturation and
heart rate. Local parenchymal perfusion (perfusion index ...
Related articles - All 13 versions
RR Liu, TH Murphy - Journal of Biological Chemistry, 2009 - ASBMB
... The MouseOx pulse oximeter (Starr Life Sciences, Oakmont, PA) was used in some
animals to monitor heart rate and oxygen saturation and was mounted on the tail
(2). Assessing Changes in Dendritic Morphology during Stroke. ...
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stanford.edu [PDF]L Xu, JF Emery, YB Ouyang, LA Voloboueva, RG … - Glia - interscience.wiley.com
... Rectal temperature was 3761.0°C controlled by a Home- othermic blanket (Harvard Apparatus,
Holliston, MA). Respiratory rate, oxygen saturation, and heart rate were monitored during surgery
with a small animal Oximeter (STARR life sciences Corp., Allison Park, PA). ...
ME Schober, B Block, JC Beachy, KD Statler… - Journal of … - liebertonline.com
... heating pad. Oxygenation, heart rate and respiratory rate were monitored using femoral probe
pulse oximetry (Mousox ®, Starr Life Sciences, Oakmont, PA). The rat was placed into a
stereotaxic frame (David Kopf, Tujunga, CA). After shaving, prepping ...
All 2 versions
I Cernak, AC Merkle, VE Koliatsos, JM Bilik… - Neurobiology of …, 2010 - Elsevier
... post-exposure. Multiple vital signs were measured non-invasively using the MouseOx
Pulse Oximeter (Starr Life Sciences Corp., Oakmont, PA) before injury, immediately
after, and at 7, 14, 21, and 30 days post-exposure. The ...
Cited by 1
Respiratory function following bilateral mid-cervical contusion injury in the adult rat
MA Lane, KZ Lee, K Salazar, BE O'Steen… - Experimental …, 2011 - Elsevier
... Blood oxygen saturation. Oxygen saturation was monitored throughout the contusion
procedure by placing a pulse oximetry probe (MouseOx, Starr Life Sciences Corp.)
on the animal's hindpaw. If an animal experienced respiratory ...
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Postnatal morphine administration alters hippocampal development in rats
CM Traudt, I Tkac, KM Ennis… - Journal of …, 2011 - Wiley Online Library
... The heart rate, pulse distension, respiratory rate, and subcutaneous tissue oxygen saturation
(SpO 2 ) were continuously monitored in representative pups (n = 6 control, n = 8 morphine) using
a rodent pulse oximeter system (MouseOx; Starr Life Sciences, Oakmount, PA ...
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MeCP2 Is Critical within HoxB1-Derived Tissues of Mice for Normal Lifespan
[HTML] from cjb.netCS Ward, EM Arvide, TW Huang, J Yoo… - The Journal of …, 2011 - neuro.cjb.net
... Pulse oximetry. Heart rate data were collected by pulse oximetry with the Mouse Ox (Starr Life
Sciences). Measurements were collected from either the tail or neck of male mice. For tail
measurements, animals were placed within a restraint tube allowing access to the tail. ...
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[HTML] Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents
[HTML] from nih.govB Lee, D Clarke, A Al Ahmad, M Kahle… - The Journal of …, 2011 - ncbi.nlm.nih.gov
Cited by 2 - Related articles - All 4 versions
6. Hypertension, Hypotension & Other Cardiovascular Disorders
- ►nih.gov
J Lin, EF Lopez, Y Jin, H Van Remmen, T Bauch, HC … - Experimental gerontology, 2008 - Elsevier
... Arterial oxygen saturation, pulse rate, breath rate, and pulse distension were all
monitored using the MouseOx ™ (STARR Life Science) to confirm comparable ...
Cited by 1 - Related articles - Web Search - All 3 versions
SI Said, SA Hamidi, KG Dickman, AM Szema, S … - genetics, 2007 - cardiology.stonybrook.edu
... O 2 saturation 25 by a special mouse oximeter (Starr Life Sciences, Allison
Park, Pa) applied to the shaved thigh. Histological ...
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KJ Cummings, KG Commons, KC Fan, … - American Journal of …, 2009 - Am Physiological Soc
... In some animals, heart rate was obtained from a pulse oximeter (Starr Life Sciences, Oakmont,
PA), which was adhered lightly to the tail with polyether material. All outputs were recorded at
1 kHz (PowerLab and Chart; ADInstruments, Colorado Springs, CO). ...
Cited by 4 - Related articles - All 7 versions
Signaling from beta-and beta 2-adrenergic receptors is defined by differential interactions with …
- ►nih.gov
W Richter, P Day, R Agrawal, MD Bruss, S Granier, … - The EMBO Journal, 2008 - nature.com
... A mouse pulse oximeter sensor (Mouse Ox, Starr Life Science Corp., Allison Park,
PA) was then placed on the thigh of the mouse, and baseline heart-rate data ...
Cited by 10 - Related articles - Web Search - BL Direct - All 4 versions
- ►ubc.ca [PDF]
R Liu - dspace.library.ubc.ca
Page 1. IN VIVO STUDY OF THE MITOCHONDRIAL DYSFUNCTION DURING ISCHEMIA AND THE
EFFECT OF OXIDATIVE STRESS ON CELL PROLIFERATION by RAN LIU ...
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Correlation of Blood Flow and Systemic Physiology in Mice Tumor Models in Photodynamic Therapy
HW Wang, S Schenkel, RC Mesquita, AG Yodh … - Biomedical …, 2010 - opticsinfobase.org
... were analyzed with a Brownian diffusion semi-infinite homogeneous medium model for the mouse
tumor and fits to the measured autocorrelation function were thus obtained [6]. Heart and breath
rates were simultaneously acquired with a vitals monitor (MouseOx) placed on the ...
R Liu - circle.ubc.ca
Page 1. IN VIVO STUDY OF THE MITOCHONDRIAL DYSFUNCTION DURING
ISCHEMIA AND THE EFFECT OF OXIDATIVE STRESS ON CELL PROLIFERATION
by RAN LIU B.Sc., The University of Toronto, 2006 A THESIS ...
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V Campanucci, A Krishnaswamy… - Neuron, 2010 - Elsevier
All 5 versions
[CITATION] Heart Rate and Electrocardiography Monitoring in Mice
D Ho, X Zhao, S Gao, C Hong… - Current Protocols in …, 2011 - Wiley Online Library
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Heart Rate and Electrocardiography Monitoring in Mice
- David Ho,
- Xin Zhao,
- Shumin Gao,
- Chull Hong,
- Dorothy E. Vatner,
- Stephen F. Vatner
Published Online: 1 MAR 2011
DOI: 10.1002/9780470942390.mo100159
Copyright © 2011 by John Wiley and Sons, Inc.
[PDF] from ajol.infoHT Liu, F Li, YM Wang, WB Lau, L Tao… - African Journal of …, 2011 - ajol.info
... Arterial oxygen saturation measurement Arterial oxygen saturation data was acquired
via the non-invasive Mouseox system (Starr Life Sciences Inc, USA), utilizing a sensor
clip placed on the hind limb or paw. The arterial oxygen ...
Related articles - All 4 versions
[PDF] from 171.66.122.149G Su, A Atakilit, JT Li, N Wu… - American Journal of …, 2011 - Am Thoracic Soc
... Pulse oximetry: Five consecutive sustained readings for at least 30 seconds were averaged using
the MouseOx® system (Starr Life Sciences, Oakmont, Pennsylvania). Primary lung endothelial
cells: Mouse lungs were perfused to clear, harvested en bloc, minced ...
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7. Hypoxia & Inhalation Studies
Physostigmine reverses cognitive dysfunction caused by moderate hypoxia in adult mice
►anesthesia-analgesia.com
A Bekker, M Haile, K Gingrich, L Wenning, A Gorny, … - Anesthesia & Analgesia, 2007 - anesthesia-analgesia.com
... We assessed arterial oxygen saturation in a separate group of mice by using a
Mouse-Ox pulse oximeter (STARR life Sciences, Allison Park, PA). ...
Cited by 2 - Related articles - Web Search - BL Direct - All 12 versions
EV Fomicheva, II Turner, TG Edwards, J Hoff, E … - Molecular …, 2008 - nature.com
... The ribs were reapproximated and incision closed in two layers. Postoperative care was continued
using blood oxygen monitoring (Mouse Ox Starr Life Sciences, Allen Park, PA) until extubation
and full recovery from anesthesia. In vivo imaging of luciferase activity. ...
Cited by 4 - Related articles - All 4 versions
Aerosolized Phosphoinositide 3-Kinase γ/δ Inhibitor TG100-115 [3-[2, 4-Diamino-6-(3-hydroxyphenyl) …
J Doukas, L Eide, K Stebbins, A Racanelli-Layton, … - Journal of Pharmacology and Experimental Therapeutics, 2009 - ASPET
... Arterial oxygenation levels were monitored using a pulse oximeter (Starr
Life Sciences, Oakmont, PA) to ensure proper ventilation. ...
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Development of the ACTH and corticosterone response to acute hypoxia in the neonatal rat
ED Bruder, JK Taylor, KJ Kamer, H Raff - American Journal of Physiology- Regulatory, Integrative and …, 2008 - Am Physiological Soc
... Arterial O 2 saturation (SPO 2 ; %) and heart rate (bpm) were measured using the
MouseOx pulse oximetry unit (Starr Life Sciences, Allison Park, PA). ...
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Epidermal sensing of oxygen is essential for systemic hypoxic response
- ►shmu.edu.cn [PDF]
AT Boutin, A Weidemann, Z Fu, L Mesropian, K … - Cell, 2008 - Elsevier
Cited by 7 - Related articles - Web Search - All 5 versions
HC O'Neill, CW White, LA Veress, TB Hendry- … - Free Radical Biology …, 2010 - Elsevier
... Pulse Oximetry The MouseOx pulse oximeter (Starr Life Sciences, Oakmont PA), with a rat infrared
sensor collar clip, was used to measure arterial hemoglobin oxygen saturation rats before CEES
inhalation and at 18 hours post inhalation, immediately prior to euthanasia. ...
Cited by 1 - Related articles - All 2 versions
Effect of intermittent hypoxia on atherosclerosis in apolipoprotein E-deficient mice
J Jun, C Reinke, D Bedja, D Berkowitz, S Bevans-Fonti, … - Atherosclerosis, 2009 - Elsevier
... 20.9%. Oxygen level was measured with a ProOx 110 analyzer (Biospherix, Redfield,
NY) and pulse oximetry with a neck cuff (Starr Life Sciences Corp., Oakmont, PA).
2.3. Blood pressure and pulse wave velocity (PWV). Blood ...
Cited by 1 - Related articles - All 3 versions
Nimodipine prevents transient cognitive dysfunction after moderate hypoxia in adult mice
M Haile, F Limson, K Gingrich, YS Li, D … - Journal of …, 2009 - journals.lww.com
... mg/kg of NIMO or vehicle in a 0.25 mL solution. Mice were given the ORT once either
on Day 1 or Day 7. Separate groups of mice were used to collect data on O 2
saturation (MouseOx, STARR Life Sciences, Allison Park, PA). ...
Cited by 4 - Related articles - All 3 versions
Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction
RM Douglas, J Ryu, A Kanaan, MC … - American Journal of …, 2010 - Am Physiological Soc
... unrestrained un- 140 anaesthetized mice (n = 4) either in room air or in the
environmental chamber using the 141 MouseOx system (Starr Life Sciences Corp,
Oakmont, PA) as per manufacture's instruction. 142 Data was collected ...
NJ Marcus, YL Li, CE Bird, HD Schultz, BJ … - Respiratory Physiology & …, 2010 - Elsevier
... 2.6. Physiological measurements. Blood pressure, arterial oxygen saturation (Sa O 2 ; MouseOx,
Starr Life Sciences, Oakmont, PA), and end-tidal CO 2 (PET CO 2 ; Capnogard, Respironics
Novametrix, Wallingford, CT) were measured continuously during the experiment. ...
Related articles - All 2 versions
A Tadjalli, J Duffin… - Journal of Neuroscience, 2010 - neuro.cjb.net
... Measuring CO 2 and O 2 levels. End-tidal CO 2 was monitored using a CO 2 analyzer (17630;
VacuMed). Arterial O 2 saturation was measured using a pulse oximeter designed for rodents
(MouseOx Pulse Oximeter; STARR Life Sciences Corp.). ...
JR Skelly, D Edge, CM Shortt, JFX Jones… - Respiratory Physiology …, 2011 - Elsevier
... Chamber O 2 concentration was measured continuously using an ML205 gas analyser (AD
Instruments) from an exit port in the chamber. Physiological indices were measured using a
MouseOx™ pulse oximeter (Starr Life Sciences Corporation). View Within Article. 2.3. ...
J Cai, CM Tuong… - Respiratory physiology & neurobiology, 2011 - Elsevier
... Arterial oxygen saturation (S p O 2 ), respiratory rate, and cardiac pulse rate were
recorded on unanesthetized P2 to P7 IA- or IH-treated pups using the MouseOx
Pulse Oximeter (STARR Life Sciences Corp., Oakmont, PA). ...
Cited by 1 - Related articles - All 3 versions
H Daijo, S Kai, T Tanaka, T Wakamatsu… - European journal of …, 2011 - Elsevier
... heart rate, and oxygen saturation of arterial haemoglobin (SpO2) during experiments were
measured using a tail-cuff sphygmomanometer (model MK-1030, Muromachi Kikai, Tokyo, Japan)
(Shiuchi et al., 2002) and MouseOx pulse oximeter (Starr Life Sciences, Oakmont, PA ...
All 3 versions
R Tiede, K Krautwald, A Fincke… - Journal of Cerebral Blood …, 2011 - nature.com
... Heating was provided from the ventral side and breathing rate, heart rate, and oxygen
saturation were monitored during the whole experiment using an MRI-compatible pulse
oxymeter (MouseOx, Starr Life Sciences, Pittsburgh, PA, USA). ...
S Kai, T Tanaka, H Daijo, H Harada… - … & Redox Signaling, 2011 - liebertonline.com
... Blood pressure, heart rate, and peripheral O 2 saturation (SpO 2 ) during experiments were
measured with a tail-cuff sphygmomanometer (model MK-1030; Muromachi Kikai, Tokyo, Japan)
(41) and a MouseOx pulse oximeter (Starr Life Sciences, Oakmont, PA) (5). At the end of ...
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Hypoxia-induced angiogenesis is delayed in aging mouse brain
GF Benderro, JC LaManna - Brain research, 2011 - Elsevier
... 4.2. Arterial oxygen saturation measurement Arterial oxygen saturation was assessed in a group
of mice kept in normoxia or 7 days of hypoxia by using a Mouse-Ox pulse oximeter (STARR Life
Sciences Corp., Oakmount, PA).These mice were anesthetized with isoflurane (2.5 ...
Cited by 1 - Related articles - All 4 versions
8. Vital Signs Monitoring During Imaging
Quantitative two-photon imaging of blood flow in cortex
JD Driscoll, AY Shih, PJ Drew, I Valmianski, D … - physics.ucsd.edu
... Isoflurane vaporizer (IsoTec) - Periosteal elevator (Roboz) - Pulse oximeter (Nonin
for rats; Starr Life Sciences for mice) - Screwdriver, miniature ...
Two-Photon Imaging during Prolonged Middle Cerebral Artery Occlusion in Mice Reveals Recovery of …
- ►jneurosci.org
P Li, TH Murphy - Journal of Neuroscience, 2008 - Soc Neuroscience
... In addition to measuring the heart rate electrophysiologically (in most animals),
we also assessed physiological parameters using a Starr Life Sciences Mouse ...
Related articles - Web Search - All 3 versions
Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic …
- ►cjb.net
TH Murphy, P Li, K Betts, R Liu - Journal of Neuroscience, 2008 - neuro.cjb.net
... In addition to measuring the heart rate electrophysiologically, we also assessed
physiological parameters using a Starr Life Sciences (Oakmont, PA) Mouse-Ox ...
Cited by 10 - Related articles - Web Search - All 4 versions
Basics of Small Animal Handling for In Vivo Imaging
LW HEDLUND, TL GLUCKMAN - Molecular Imaging in Oncology, 2008 - books.google.com
... cardiac pulse, breathing rate, and oxygen saturation from a single sensor applied
to the thigh or tail of a mouse or rat (Starr Life Sciences Corporation ...
Related articles - Web Search
Characterization And Feasibility Study Of A Near Infrared CCD Imager For Monitoring Tumor …
- ►uta.edu [PDF]
M Goel, H Liu - 2007 - dspace.uta.edu
Page 1. CHARACTERIZATION AND FEASIBILITY STUDY OF A NEAR INFRARED CCD IMAGER
FOR MONITORING TUMOR HEMODYNAMICS by MANAN GOEL Presented ...
Related articles - View as HTML - Web Search - All 5 versions
Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal …
- Free from Publisher
M Egeblad, AJ Ewald, HA Askautrud, ML Truitt, BE … - Disease Models & Mechanisms, 2008 - pubmedcentral.nih.gov
... We used an oximeter probe (MouseOx, Starr Life Sciences, PA) to monitor and display
the heart rate (beats per minute; bpm), the arterial oxygen saturation of ...
Cited by 3 - Related articles - Web Search - All 6 versions
S Zhang, TH Murphy - PLoS Biol, 2007 - biology.plosjournals.org
... The physiological parameters mentioned above were measured using a Starr Life Sciences
Mouse-Ox pulse oximeter (http://www.starrlifesciences.com). ...
Cited by 12 - Related articles - Web Search - All 6 versions
New Method to Quantify Angiogenesis in vivo Using Multi-photon Imaging
BJ Herron, JS Smith, RW Cole - Microscopy Today, 2009 - Cambridge Univ Press
... dextrose in 0.9% NaCl. Vital signs, including pulse, respiration, and oxygen saturation
were monitored with the MouseOx system (Starr Life Science Corp.) throughout
all procedures. Imaging. Individual mice were restrained ...
Related articles
Quantitative two-photon imaging of blood flow in cortex
JD Driscoll, AY Shih, PJ Drew, I … - … in Neuroscience and …, 2010 - physics.ucsd.edu
... 1A) - Heat pad, feedback regulated (Harvard for rats; FHC for mice) - Hemostats - Isoflurane
vaporizer (IsoTec) - Periosteal elevator (Roboz) - Pulse oximeter (Nonin for rats; Starr Life
Sciences for mice) - Screwdriver, miniature - Stereotaxic frame (Kopf) Imaging equipment ...
Cited by 1 - Related articles - View as HTML - All 2 versions
F Angenstein, K Krautwald, H Scheich - NeuroImage, 2010 - Elsevier
... Heating was provided from the ventral side and heart rate, breathing rate, and oxygen
saturation was monitored during the whole experiment using an MRI-compatible pulse
oxymeter (MouseOx™, Starr Life Sciences Corp. Pittsburgh PA, USA). ...
All 2 versions
Micro-CT imaging assessment of dobutamine-induced cardiac stress in rats
CT Badea, LW Hedlund, J Cook, BR Berridge, … - … of Pharmacological and …, 2010 - Elsevier
... Instruments, Austin, TX). Additionally, heart and breathing rates, pulse and breathing
distentions, and oxygen saturation were monitored by a pulse oximeter placed on
the hind paw (MouseOx, StarrLife Sci, PA). Pulse distention ...
Dendra2 Photoswitching through the Mammary Imaging Window
B Gligorijevic, D Kedrin, JE Segall, J Condeelis, … - Journal of Visualized …, 2009 - jove.com
... data acquisition). The MouseOx pulse oximetry system (Starr life Sciences Corp)
has been used succesfully. That way the data can be gathered continuously without
turning the lights on in the room to check on the animal. Note ...
Cited by 2 - Related articles - Cached - All 5 versions
SO Park, M Wankhede, YJ Lee, EJ Choi, N Fliess, SW … - 2009 - ncbi.nlm.nih.gov
... O 2 saturation data. Oxygen saturation was measured by pulse oximeter (MouseOx;
Starr Life Sciences Corp.). The mouse was placed on a restrainer without anesthesia,
and the sensory clip was placed on a hind paw. The ...
Cited by 6 - Related articles - All 8 versions
RM Paredes, JC Etzler, LT Watts, W Zheng, JD … - Methods, 2008 - Elsevier
Cited by 12 - Related articles - All 5 versions
Cooperative regulation of neurotransmitter release by Rab3a and synapsin II
WL Coleman, M Bykhovskaia - Molecular and Cellular Neuroscience, 2010 – Elsevier
Laser speckle contrast imaging of collateral blood flow during acute ischemic stroke
GA Armitage, KG Todd, A Shuaib… - Journal of Cerebral Blood …, 2010 - nature.com
... 24 hours imaging sessions), rats were anesthetized with 1.5% to 2.0% isoflourane (30:70, O 2
:N 2 0). Temperature was maintained at 36.7°C, and heart rate, oxygen saturation, and breath
rate were monitored using a MouseOx pulse oximeter (STARR Life Sciences, Oakmont ...
Related articles - All 4 versions
N Li, G Pelled… - Engineering in Medicine and …, 2010 - ieeexplore.ieee.org
... Animal body temperature was maintained throughout using a Mega Warmers pad
(Grabber Inc. MI.). Respiration rate, PO2 and heart rate were continuously monitored
by an oximeter (MouseOx, STARR Life Sciences Corp., PA.). ...
Imaging retinal blood flow with laser speckle flowmetry
AI Srienc, ZL Kurth-Nelson… - neuroscience.umn.edu
... Blood oxygen saturation level and heart rate (MouseOx, Starr Life Sciences Corp),
arterial blood pressure (Pressure Monitor BP-1, World Precision Instruments), and
end-tidal CO2 (microCapStar, CWE) were monitored continuously. ...
Related articles - View as HTML
BH De La Garza, ER Muir, G Li, YY Shih… - NMR Biomed, 2010 - ric.uthscsa.edu
... setting (19). The rectal temperature was maintained at 37.0 + 0.58C. The heart rate and
blood oxygen saturation level were monitored using a MouseOx system (STARR Life
Science Corp., Oakmont, PA, USA). All recorded physiological ...
Cited by 1 - Related articles - View as HTML
H Igarashi, VJ Huber, M Tsujita… - Neurological Sciences - Springer
... anesthesia period. Oxygen saturation (SpO2) was monitored throughout the operation
procedure using a pulse oxymeter Mouse Ox (STARR Life Sciences Co, Oakmont,
PA, USA) with probe placement on the left thigh. Regional ...
Related articles
A Novel Method to Quantify Angiogenesis in vivo Using Multi-photon Imaging
R Cole, J Smith… - Microscopy and Microanalysis, 2009 - Cambridge Univ Press
... Vital signs were monitored with the MouseOx system, Starr Life Science Corp. (Oakmount PA)
throughout all procedures. Animals were given a tail vein injection of 70kD FITC conjugated
dextran (Sigma Aldrich, St, Louis MO) before each imaging session. ...
Related articles - All 2 versions
[HTML] from nih.gov H Igarashi, VJ Huber, M Tsujita… - Neurological Sciences, 2011 - Springer
... period. Oxygen saturation (SpO2) was monitored throughout the operation procedure
using a pulse oxymeter Mouse Ox (STARR Life Sciences Co, Oakmont, PA, USA)
with probe placement on the left thigh. Regional cerebral ...
Cited by 3 - Related articles - All 5 versions
Preparation of mice for long-term intravital imaging of the mammary gland
[HTML] from cshlp.org AJ Ewald, Z Werb… - Cold Spring Harbor …, 2011 - cshprotocols.cshlp.org
... Nebulizer (Salter Labs 8901), for use as a humidifier. Oximeter probe (MouseOx; STARR
Life Sciences), for imaging sessions of >3 h. Oxygen analyzer (for anesthesia gas; Hudson
RCI 5801). Oxygen sensor (for anesthesia gas; Hudson RCI 5803). ...
Cited by 2 - Related articles - All 2 versions
D Duerschmied, M Meiner, K Peter… - Investigative …, 2011 - journals.lww.com
... blood in the cavum. Throughout the procedure, oxygen saturation, respiratory rate,
and heart rate were continually monitored with a MouseOx system (Starr Life Sciences,
Oakmont, PA) and maintained within the normal ranges. ...
Related articles - All 4 versions
Two-Photon Intravital Multicolour Imaging to Study Metastatic Behaviour of Cancer Cells In Vivo.
SE Le Dévédec, W van Roosmalen, C Pont… - Methods in molecular …, 2011 - Springer
... Page 9. 339 22 Two-Photon Intravital Multicolour Imaging to Study Metastatic Behaviour… quality
due to numerous artefacts. The monitoring can be done visually, or by using the MouseOx pulse
oximetry sys- tem (Starr life Sciences Corp) as done in other laboratories. ...
All 2 versions
[HTML] Intravital Two-Photon Microscopy of Immune Cell Dynamics in Corneal Lymphatic Vessels
[HTML] from plos.org P Steven, F Bock, G Hüttmann… - PloS one, 2011 - dx.plos.org
... The animal holder was equipped with a heating device to maintain normal body temperature
and additional monitoring of the blood oxygen level, pulse and breath rate was facilitated by a
murine pulse oximeter system (MouseOx, Starr Life Sciences Corp., Pittsburgh, PA, USA). ...
Related articles - Cached - All 3 versions
[PDF] from cornell.edu J Nguyen, N Nishimura, RN Fetcho… - Journal of Cerebral …, 2011 - nature.com
... Heart rate and arterial oxygen saturation were monitored using a pulse oximeter (MouseOx; Starr
Life Sciences Corp., Oakmont, PA, USA) clipped to the rat's hind paw. Hydration was maintained
with hourly subcutaneous injections of 5% glucose (wt/vol) in saline (1 mL/kg rat). ...
Cited by 1 - Related articles - All 4 versions
[PDF] Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain
[PDF] from ucsd.edu AY Shih, JD Driscoll, PJ Drew… - Journal of Cerebral … - mayerhall.ucsd.edu
... Hemostats (no. 105-1105; George Tiemann) • Isoflurane vaporizer (IsoTec4; Ohmeda) • Pulse
oximeter (MouseOx; Starr Life Sciences) • Screwdriver, miniature (26B09.01; Garret Wade) •
Stereotaxic frame, with rat or mouse ear and bite bars (Model 900; Kopf) ...
Cited by 1 - Related articles - View as HTML - All 2 versions
R Franconville, G Revet, G Astorga… - Journal of …, 2011 - Am Physiological Soc
... A pulse oximeter probe (MouseOx Pulse Oximeter; Starr Life Sciences) was placed on the hind
leg, and the parameters reported by the system (partial O 2 pressure, heart rate, and breathing
rate) were monitored continuously throughout surgery and imaging. ...
Cited by 2 - Related articles - All 3 versions
9. Vital Signs Monitoring During Surgery & Experiments Requiring Anesthesia
Injury Modality, Survival Interval and Sample Region are Critical Determinants of qRT- …
JL Harris, T Reeves, L Phillips - Journal of Neurotrauma - liebertonline.com
... and to prevent hypoxia or hypercapnia, rats were monitored during the course of
surgery with a pulse-oximetry system (MouseOx, Starr Life Sciences, Corp.). ...
Related articles - All 3 versions
L Xu, LA Voloboueva, YB Ouyang, JF Emery, … - Journal of Cerebral …, 2008 - nature.com
... Temperature, respiratory rate, oxygen saturation, and heart rate were monitored during the
surgery, and after reanesthetizing the animals to remove the suture at 100 mins, with a small
animal Oximeter (STARR Life Sciences Corp., Allison Park, PA, USA). ...
Cited by 13 - Related articles - All 5 versions
RD Chomsung, H Wei, JD Day-Brown, HM … - Cerebral …, 2009 - Oxford Univ Press
... The heart rate was continuously monitored with a MouseOx pulse oximeter (STARR
Life Sciences Corp., Pittsburgh, PA). Prior to injection, the tree shrews were placed
in a stereotaxic apparatus and prepared for sterile surgery. ...
Related articles - All 3 versions
[BOOK] Laboratory animal anaesthesia
P Flecknell - 2009 - books.google.com
... Figure 2.23 Duration of anaesthesia and sleep times in rats with different anaesthetics CHAPTER
3 Figure 3.1 Methods of protecting an animal's eyes during anaesthesia Figure 3.2 Respiratory
monitor using a pressure sensor Figure 3.3 The 'Mouseox' pulse oximeter in use ...
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Anesthesia with Isoflurane Increases Amyloid Pathology in Mice Models of Alzheimer'S Disease
J Perucho, I Rubio, MJ Casarejos, A Gomez, JA … - Journal of Alzheimer's … - IOS Press
Page 1. 1 Journal of Alzheimer's Disease ISSN: 1387-2877 IOS Press DOI:
10.3233/JAD-2009-1318 Anesthesia with Isoflurane Increases Amyloid Pathology
in Mice Models of Alzheimer's Disease Juan Peruchoa, Isabel Rubiob ...
Cited by 1 - Related articles - All 2 versions
Mild Sensory Stimulation Completely Protects the Adult Rodent Cortex from Ischemic Stroke
CC Lay, MF Davis, CH Chen-Bee, RD Frostig… - PLoS ONE, 2010 - dx.plos.org
... Three animals were disqualified from this study due to obvious arterial abnormalities or
malformations [43], [44]. (Also, in a subset of animals, Arterial O 2 saturation, respiration, and
heart rate were measured using the MouseOx pulse oximetry unit (Starr Life Sciences, Allison ...
Cited by 1 - Related articles - Cached - All 2 versions
Limitations of collateral flow after occlusion of a single cortical penetrating arteriole
N Nishimura, NL Rosidi, C Iadecola… - Journal of Cerebral Blood …, 2010 - nature.com
... A pulse oximeter (MouseOx; Starr Life Sciences Corp., Oakmont, PA, USA) clipped to the hind
paw of the rat was used to monitor blood oxygen saturation and heart rate. A local anesthetic,
bupivacaine (0.1 mL, 0.125%), was administered at each incision site. ...
Related articles - All 3 versions
W Zheng, LT Watts, DM Holstein, SI Prajapati… - PloS one, 2010 - dx.plos.org
... Body temperature was maintained at 37°C by a feedback-controlled heating pad (Gaymar
T/Pump). Vital signs including oxygen saturation, respiratory rate, and heart rate were
continuously monitored by using the MouseOx system (STARR Life Sciences). ...
Cached
YYI Shih, HY Wey, BH De La Garza… - Journal of Cerebral Blood …, 2010 - nature.com
... 2003). Rectal temperature was maintained at 37.0°C±0.5°C using a circulating
warm-water pad. Heart rate and blood oxygen saturation level were monitored using
MouseOx system (STARR Life Science, Oakmont, PA, USA). All ...
K Coppieters, MM Martinic, WB Kiosses, N Amirian… - PloS one, 2010 - ncbi.nlm.nih.gov
... instruments). Heart rate and arterial oxygen saturation were monitored using a
MouseOx pulse oximeter (Starr Life Sciences Corp) and were found to be similar in
animals undergoing surgery as compared to anesthetized controls. ...
Effects of D-3-hydroxybutyrate treatment on hypoglycemic coma in rat pups
PW Schutz, PKH Wong, J O'Kusky, SM Innis… - Experimental …, 2010 - Elsevier
... Heart rate and oxygen saturation were measured by pulse oximetry (MouseOx, Starr Life
Sciences, USA). Temperature was monitored with a rectal probe attached to a PowerLab data
acquisition system (ADInstruments, USA). Electroencephalography. ...
Glutamate transporter type 3 knockout reduces brain tolerance to focal brain ischemia in mice
L Li… - Journal of Cerebral Blood Flow & Metabolism, 2010 - nature.com
... Heart rate, breathing rate, and arterial blood oxygen saturation of mice were monitored
continuously and noninvasively using a MouseOX Murine Plus Oximeter System (Starr
Life Sciences Corporation, Oakmont, PA, USA) during the surgery. ...
A Selvamani… - Journal of Neuroscience, 2010 - Soc Neuroscience
... (2) For delayed IGF-1 administration, IGF-1 was administered 4 h after the ET-1 injection. During
surgery, the rats were maintained at 37°C throughout, and oxygen saturation and respiratory
rate were constantly monitored using the Mouse Oximeter (STARR Life Sciences). ...
Cited by 1 - Related articles - All 3 versions
Anesthetic Considerations for the Study of Murine Tumor Models
T Schroeder, S Shan… - Tumor Models in Cancer Research, 2011 - Springer
... However, the proper control of anesthesia depth may require expensive machinery,
such as an animal pulse oxymeter (eg MouseOx, STARR Life Sciences, Oakmont,
PA). In addition, a calibrated anesthesia machine is necessary. ...
T Horn… - Neurochemistry International, 2010 - Elsevier
... in brain slices. 2.5 Physiological parameters Blood oxygen saturation in awake and
anesthetized mice was determined with the help of a MouseOx pulse oximeter (Starr
Life Sciences, Oakmont, PA, USA). Cerebral blood flow ...
Duration of Anesthesia Affects Intraocular Pressure, But Not Outflow Facility in Mice
LJ Camras, KE Sufficool, CB Camras… - Current Eye …, 2010 - informahealthcare.com
... Supplemental doses were administered as needed. A sensor clip was placed on the
mouse's thigh to obtain oxygen saturation and heart rate (Mouse Ox ™ , Revision 5.1,
STARR Life Sciences Corp, Oakmont, Pennsylvania, USA). ...
Related articles - All 3 versions
Pulvinar Projections to the Striatum and Amygdala in the Tree Shrew
JD Day-Brown, H Wei, RD Chomsung… - Frontiers in …, 2010 - ncbi.nlm.nih.gov
... Prior to injection, the tree shrews were placed in a stereotaxic apparatus and prepared
for sterile surgery. The heart rate was continuously monitored with a MouseOx pulse
oximeter (STARR Life Sciences Corp., Pittsburgh, PA, USA). ...
State-specific Effects of Sevoflurane Anesthesia on Sleep Homeostasis
M Sleep - Anesthesiology, 2011 - pdfs.journals.lww.com
... The heart rate, respiratory rate, and oxygen saturation were con- tinuously monitored using
a MouseOx® monitor (Starr Life Ad libitum sleep Ad libitum sleep Electrophysiological
recordings Experimental condition Ad libitum (recovery) sleep ...
Assessment of glial function in the in vivo retina.
AI Srienc, TE Kornfield, A Mishra, MA Burian… - Methods in molecular …, 2012 - Springer
... 3. End-tidal CO 2 monitor (microCapStar, CWE). 4. Ventilator (CWE SAR-830-P). 5. Blood gas
analyzer (Radiometer, ABL 800 Flex). 6. Pulse oximeter (MouseOx, Starr Life Sciences Corp.).
7. Thermostatically controlled heater (TC-1000 Temperature Controller, CWE). ...
Chronic assessment of diaphragm muscle EMG activity across motor behaviors
CB Mantilla, YB Seven, JN Hurtado-Palomino… - Respiratory physiology …, 2011 - Elsevier
... In a subset of animals, non-invasive measurements of arterial oxygenation (MouseOX,
Starr Life Sciences Corp., Oakmont, PA) verified that hemoglobin oxygen saturation
returned to baseline during the recovery period between behaviors. ...
Related articles - All 3 versions
I Hahn, A Klaus, AK Janze, K Steinwede… - Infection and …, 2011 - Am Soc Microbiol
... invasive, real-time pulse oximetry (MouseOx®, STARR Life Sciences, Oakmont, 179 USA). ...
connected to the mouse Ox system, according to the manufacturer's instructions. 183 ... ly using
the MouseOx® software package. Uninfected control mice (day 0) of either 186 ...
All 5 versions
Lumbosacral sensory neuronal activity is enhanced by activation of urothelial purinergic receptors
A Munoz, GT Somogyi, TB Boone… - Brain Research Bulletin, 2011 - Elsevier
... A Mouse-Ox rat collar clip (STARR Life Sciences, Oakmont, PA) was used to non-invasively
monitor arterial oxygen saturation and pulse rate. 2.5. Data analysis and statistics. The analysis
in this study only involved individual rats that went through all three experimental steps. ...
Related articles - All 2 versions
[HTML] from plos.org WC Risher, MR Lee, IV Fomitcheva, DC Hess… - PloS one, 2011 - dx.plos.org
... Craniotomy for the optical window followed standard protocol [15]. Mice were anesthetized with
an intraperitoneal injection of urethane (1.5 mg/g body weight) with heart rate monitored
(450–650 beats/min) using MouseOx® pulse oximeter (STARR Life Sciences). ...
Related articles - Cached - All 3 versions
A micro-advancer device for vitreal injection and retinal recording and stimulation
D Hultman… - Experimental Eye Research, 2011 - Elsevier
... Blood oxygen saturation level and heart rate (MouseOx, Starr Life Sciences Corp),
arterial blood pressure (Pressure Monitor BP-1, World Precision Instruments), and
end-tidal CO 2 (microCapStar, CWE), are continuously monitored. ...
Related articles - All 2 versions
GF Alheid, W Jiao… - Neuroscience, 2011 - Elsevier
... abdomen. Oxygen saturation as well as heart rate and respiratory rate were monitored
via a pulse oximeter (Mouse Ox, Starr Life Sciences). In a subset of rats a femoral artery
was cannulated (PE-50) for monitoring arterial pressure. ...
Cited by 1 - All 3 versions
[HTML] from molecularpain.comCL Renn, VA Carozzi, P Rhee, D Gallop… - Molecular …, 2011 - molecularpain.com
... the surgical site. Throughout both procedures, the mice continued to breathe
spontaneously at ~2-3 Hz and the heart rate was maintained at ~9-10 Hz (MouseOx,
STARR Life Sciences Corp., Oakmont, PA). The core body temperature ...
Related articles - Cached - All 6 versions
MT Koltz, C Tosun, DB Kurland… - Journal of …, 2011 - thejns.org
... Dams were anesthetized with 3% isoflurane delivered with 75% air + 25% O 2 ; anesthesia was
maintained with 2% isoflurane for the duration of surgery. Pulse oximetry (Mouse-Ox; STARR
Life Sciences Corp.) was used to maintain an O 2 saturation of 90%–95%. ...
Degeneration of cortical function in the Royal College of Surgeons rat
C Gias, A Vugler, J Lawrence, AJ Carr, LL Chen… - Vision Research, 2011 - Elsevier
... Blood oxygen saturation and heart rate were monitored non-invasively with a
MouseOx (Starr Life Sciences Corp, Oakmont, PA, USA). Data presented in this study
was taken with average blood oxygen saturation above 90%. ...
All 3 versions
Developmental Changes in Short-Term Plasticity at the Rat Calyx of Held Synapse
[HTML] from cjb.netTTH Crins, SI Rusu… - The Journal of …, 2011 - Soc Neuroscience
... 56. Arterial oxygen saturation and heart rate were monitored using a MouseOx
(STARR Life Sciences). The left MNTB was reached via a ventral approach, as
previously described (Rodríguez-Contreras et al., 2008). Typically ...
Cited by 1 - Related articles - All 4 versions
Brain‐derived neurotrophic factor modulates antiretroviral‐induced mechanical allodynia in the mouse
CL Renn, CC Leitch, S Lessans… - Journal of …, 2011 - Wiley Online Library
... noxious stimulus. Throughout the procedure, the mice continued to breathe
spontaneously at ∼2–3 Hz, and the heart rate was maintained at ∼9–10 Hz
(MouseOx; STARR Life Sciences, Oakmont, PA). Local anesthesia was ...
Related articles - All 2 versions
10. Pharmacology & Toxicology
A novel paradigm for assessing efficacies of potential antidotes against neurotoxins in mice
- ►nih.gov
DL Crankshaw, DJW Goon, JE Briggs, D DeLong, M … - Toxicology letters, 2007 - Elsevier
... 5. Measurements were taken with a Starr Life Sciences mouse oximeter light cuff
and consisted of repeated measures at 0, 15, and 30 min post-CN. ...
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Historically, antidotal potencies of cyanide antagonists were measured as increases in the experimental LD(50) for cyanide elicited by the antidotes. This required the use of high doses of cyanide following pre-treatment with the putative antidote. Since IACUC guidelines at our institutions strongly discourage LD(50) determinations: we developed a new test paradigm that allowed for maximal survival of cyanide-treated animals with greatly reduced numbers of animals. Symptoms of cyanide toxicity include disruption of neuromuscular coordination, i.e., the righting reflex. Therefore, to establish a dose-response curve, the times required for recovery of this righting reflex with increasing doses of cyanide were measured. A cyanide dose that disrupted this righting reflex for approximately 1h with minimal deaths was then selected. Using this paradigm, the current cyanide antidotes, viz., nitrite plus thiosulfate and hydroxocobalamin, as well as some potential cyanide antidotes that we developed, were evaluated pre- and post-cyanide. This allowed, for the first time, the assessment of the post-cyanide effectiveness of the current antidotes against cyanide poisoning in a live animal. In addition, some prototype compounds were found to exhibit antidotal efficacy not only when injected i.p. following cyanide, but also when administered orally 30 min before cyanide. Pre-cyanide oral efficacy suggests that such compounds have the potential of being administered prophylactically before exposure to cyanide. This new test paradigm was found to be a powerful tool for assessing the efficacies of some novel antidotes against cyanide and should be equally applicable for evaluating putative antidotes for other neurotoxins.
Novelty-evoked activity in open field predicts susceptibility to helpless behavior
E Padilla, J Shumake, DW Barrett, G Holmes… - Physiology & …, 2010 - Elsevier
... Using a Mouse Ox oximeter (Starr Life Sciences Corp, Oakmont, PA), pulse rates
were measured via cyclic changes in absorption of light energy from red and infrared
LEDs (light emitting diodes) as it passed through the tissue. ...
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LK Cambal, MR Swanson, Q Yuan… - Chemical Research …, 2011 - ACS Publications
... Measurement of Oxygen Saturation, Heart Rate and Respiratory Rate. A MouseOx® Pulse
Oximeter (manufactured by STARR Life Sciences Corp.) was employed with a subset of mice
to record physiologic data in response to NaCN and/or NaNO2. The data were ...
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11. Anesthesia and Surgical Research
Monitoring of vital signs for long-term survival of mice under anesthesia
AJ Ewald, Z Werb… - Cold Spring Harbor …, 2011 - cshprotocols.cshlp.org
... Forceps (sterile). Nebulizer (Salter Labs 8901), for use as a humidifier. Oximeter probe
(MouseOx; STARR Life Sciences). Oxygen analyzer (for anesthesia gas; Hudson RCI
5801). Oxygen sensor (for anesthesia gas; Hudson RCI 5803). ...
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Anesthesia protocols for mice have been optimized, as described here, to achieve long-term imaging (up to 40 h) and facilitate survival through careful monitoring of the mice during anesthesia. Isoflurane anesthesia is the preferred method, because it can be adjusted quickly as needed during the experiment. Critical for the long survival times under anesthesia is the use of the lowest possible dose of anesthesia, which is identified by corneal reflex and monitoring of breath and heart rate, blood-oxygenation levels, and vascular distension using an oximeter probe. It is critical that the carrier gas for isoflurane is humidified. In addition, it is essential to keep mice warm and to compensate for loss of fluid by supplementing with saline. Alternative approaches rely on injectable anesthetics, which do not require dedicated equipment or high-ventilation rates in the imaging room. However, injectable anesthetics are harder to dose for image sessions of >6-10 h.
Dynamic determination of oxygenation and lung compliance in murine pneumonectomy
BC Gibney, GS Lee, JP Houdek… - Experimental Lung …, 2011 - informahealthcare.com
... The MouseOx (STARR Life Sciences, Oakmont, PA) is a pulse oximeter with a proprietary
plethysmographic waveform analysis algorithm optimized for rats and mice. The MouseOx
photodiode was placed on the shaved skin overlying either the neck or proximal thigh. ...
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Thoracic surgical procedures in mice have been applied to a wide range of investigations, but little is known about the murine physiologic response to pulmonary surgery. Using continuous arterial oximetry monitoring and the FlexiVent murine ventilator, the authors investigated the effect of anesthesia and pneumonectomy on mouse oxygen saturation and lung mechanics. Sedation resulted in a dose-dependent decline of oxygen saturation that ranged from 55% to 82%. Oxygen saturation was restored by mechanical ventilation with increased rate and tidal volumes. In the mouse strain studied, optimal ventilatory rates were a rate of 200/minute and a tidal volume of 10 mL/kg. Sustained inflation pressures, referred to as a “recruitment maneuver,” improved lung volumes, lung compliance, and arterial oxygenation. In contrast, positive end-expiratory pressure (PEEP) had a detrimental effect on oxygenation; an effect that was ameliorated after pneumonectomy. These results confirm that lung volumes in the mouse are dynamically determined and suggest a threshold level of mechanical ventilation to maintain perioperative oxygen saturation.
Read More: http://informahealthcare.com/doi/abs/10.3109/01902148.2011.561399
Anesthetic Considerations for the Study of Murine Tumor Models
T Schroeder, S Shan… - Tumor Models in Cancer Research, 2011 - Springer
... However, the proper control of anesthesia depth may require expensive machinery,
such as an animal pulse oxymeter (eg MouseOx, STARR Life Sciences, Oakmont,
PA). In addition, a calibrated anesthesia machine is necessary. ...
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D Pal, ME Walton, WJ Lipinski, LG Koch… - Anesthesia & …, 2011 - IARS
... Pump, Gaymar Industries Inc., Orchard Park, NY). The heart rate and oxygen saturation
were continu- ously monitored using a MouseOx monitor (Starr Life Sciences, Corp.,
Oakmont, PA). The animal was equili- brated to either ...
K Krautwald… - Journal of Cerebral Blood Flow & …, 2011 - nature.com
... Heating was provided from the ventral side and heart rate, breathing rate, and oxygen
saturation was monitored during the entire experiment using an MRI-compatible pulse
oxymeter (MouseOx, Starr Life Sciences Corp., Pittsburgh, PA, USA). ...
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