Hypoxia & Inhalation Studies


Monitoring Hypoxia Induced Changes in Cochlear Blood Flow and Hemoglobin Concentration Using a Combined Dual-Wavelength Laser Speckle Contrast Imaging and Doppler Optical Microangiography System

.. Body temperature was maintained at 37.0°C ± 0.5. End-tidal CO 2 (V9004 capnograph; Surgivet, Waukesha, Wis), heart rate, and blood oxygen saturation (MouseOx; Starr Life Science, Oakmont, Pa) were monitored and kept within physiologic ranges. … Purpose: To develop high-spatial-resolution magnetic resonance (MR) microangiography techniques to image the rat ocular circulation. Materials and Methods: […]

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Thermoneutrality Modifies the Impact of Hypoxia on Lipid Metabolism

.. cage 96 accompanied by four un-instrumented mice. Mouse oxygen saturation (SaO2) and breath rate were 97 measured using a MouseOx neck cuff and StarrLink Hypoxia has been shown to rapidly increase triglycerides in mice by decreasing plasma lipoprotein clearance. However, the usual temperature of hypoxic exposure is below thermoneutrality for mice, which may increase […]

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