Circulating endothelial progenitor cells are reduced in rat oxygen-induced retinopathy despite a retinal SDF-1/CXCR4 and VEGF proangiogenic response

.. Low Flow Bird MicroBlender (Care Fusion, San Diego, CA, USA) and HypoxyDial (STARR Life Sciences, Oakmont, PA, USA) blenders were used. Oxygen levels were continuosly monitored with Oxydig monitor (Drägerwer AG, Lübeck, Germany). … Aims The purpose of this study is to investigate circulating endothelial progenitor cells (EPCs) and the signaling pathways involved in […]

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Phosphorescent nanoparticles for quantitative measurements of oxygen profiles in vitro and in vivo

Abstract We present the development and characterization of nanoparticles loaded with a custom phosphor; we exploit these nanoparticles to perform quantitative measurements of the concentration of oxygen within three-dimensional (3-D) tissue cultures in vitro and blood vessels in vivo. We synthesized a customized ruthenium (Ru)-phosphor and incorporated it into polymeric nanoparticles via self-assembly. We demonstrate […]

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