Vital Signs Monitoring During Surgery & Experiments Requiring Anesthesia

… These electrodes also recorded diaphragm EMG prior to paralyzing the animals (see below). Oxygen saturation as well as heart rate and respiratory rate were monitored via a pulse oximeter (Mouse Ox, Starr Life Sciences, Oakmont, PA, USA). … Leptin decreases food intake and increases energy expenditure. Leptin administration into the CNS of mice or […]

… For measurement of peripheral blood oxygen saturation, mice were anesthetized with a 3 minute isoflurane challenge and a mouse-OX (Starr Life Science) oximeter probe was placed on the scruff of the neck to determine the oxygen saturation. … Ribs are primarily made of cortical bone and are necessary for chest expansion and ventilation. Rib […]

… In addition to DIAm EMG recordings, respiratory rate and blood O 2 levels were also measured using a pulse oximeter (MouseOX, Starr Life Sciences Corp., Oakmont, PA). A return to baseline respiratory rate and normoxic levels … We hypothesized that a shift in diaphragm muscle (DIAm) EMG power spectral density (PSD) to higher frequencies […]

… In addition, oxygen saturation, heart rate, and respiratory rate were measured and maintained within physiologic limits throughout using a noninvasive mouseOX (Starr Life Science Corp.) pulse oximeter sensor attached to the foot. … We have investigated the opioid receptor (OR) agonist (20R)-4,5-α-epoxy-6-(2-18F-fluoroethoxy)-3-hydroxy-α,17-dimethyl-α-(2-phenyleth-1-yl)-6,14-ethenomorphinan-7-methanol (18F-FE-PEO) as a candidate OR PET ligand. This tracer is attractive because […]

The neuropeptides orexins and their G protein-coupled receptors, OX1 and OX2, were discovered in 1998, and since then, their role has been investigated in many functions mediated by the central nervous system, including sleep and wakefulness, appetite/metabolism, stress response, reward/addiction, and analgesia. Orexins also have peripheral actions of less clear physiological significance still. Cellular responses […]

… The breath rate, heart rate and oxygen saturation was monitored (MouseOx, Starr Life Science Corp, Oakmont, PA, USA) and be kept in the range of 45-65 bpm, 300-400 bpm, and >90% during the surgery, respectively (Table 3). With the aid of an operating microscope, the left … Ischemic stroke accounts for over 80% in […]